Risk factors of subclinical atherosclerosis of obesity women
Autor: | G.A. Chumakova, E. S Osipova, N.G. Veselovskaya, N. N Shenkova, A. V Ott |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
cardiovascular risk
medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system Waist lcsh:RC648-665 Apolipoprotein B biology business.industry subclinical atherosclerosis Adipokine Adipose tissue visceral obesity medicine.disease Obesity Gastroenterology lcsh:Diseases of the endocrine glands. Clinical endocrinology lcsh:RC666-701 Internal medicine Subclinical atherosclerosis medicine biology.protein Ghrelin medicine.symptom business Abdominal obesity |
Zdroj: | КардиоСоматика, Vol 8, Iss 2, Pp 44-50 (2017) |
ISSN: | 2658-5707 2221-7185 |
Popis: | Research objective: study the metabolic risk factors (RF) of subclinical atherosclerosis of obese women. Material and methods. 89 women have been included in research, 50.6±6.6 years old with abdominal obesity and waist circumference >80 cm without coronary heart disease and atherosclerosis of other localisation. According to the results of the ultrasound study of brachiocephalic arteries (BCA), two groups were formed for comparison: Group 1 (n=60) without atherosclerosis BCA, Group 2 (n=29) with atherosclerosis BCA. Definitions of classical and additional metabolic RF, of adipokines of visceral adipose tissue (VAT) and ghrelin were spent to the surveyed patients. The thickness of epicardial fat (tEF) was defined at transthoracic echocardiography. Results. In the group 2 there were the highest indexes of: LDL 3.7 (2.9; 4.6) mmol/L, Apo B 1.32±0.29 g/L, CRP 2.8±0.96 mg/l, leftin 20.0 (16.4; 23.1) ng/ml, tEF 7 (6; 8) mm; lower indexes of Apo A1 1.16±0.31 g/l and ghrelin 40.7 (39.1; 42.8) pg/dl. Conclusion. The signs of subclinical atherosclerosis of the carotid arteries of obese women were associated with higher amount of VAT (tEF), inflammatory activity of plasma (CRP) and neurohumoral disorders (leftin, ghrelin). |
Databáze: | OpenAIRE |
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