Popis: |
Literature data on the role and significance of phagocytic component, in particular, neutrophils in realization of immune response of an organism to antigen are analyzed. A special attention is paid to approaches to evaluation of functional state and reactivity of phagocytes. The most informative and objective method for evaluation of functional state of neutrophils is NBT-test. NBT-test allows to evaluate a potential maximal ability of neutrophils (stimulation test), what part of maximal ability neutrophils realize at the moment of examination (spontaneous test), degree of additional activation of neutrophils in response to antigen stimulation. Spectrophotometric modification of NBT-test permits to carry out many determinations simultaneously. |