Tufted hair folliculitis: complete enduring response after treatment with rifampicin
| Autor: | A. Di Napoli, Guglielmo Pranteda, Ugo Bottoni, E. Palese, Miriam Grimaldi |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
staphylococcus aureus
medicine.medical_specialty medicine.drug_class Antibiotics Erythromycin Folliculitis Dermatology rifampicin Humans Medicine Antibacterial agent tufted hair folliculitis biology medicine.diagnostic_test business.industry Middle Aged biology.organism_classification medicine.disease Anti-Bacterial Agents Surgery medicine.anatomical_structure Scalp Dermatoses Scalp Skin biopsy Female Staphylococcal Skin Infections Rifampin business Cabello Rifampicin medicine.drug |
| Zdroj: | Journal of Dermatological Treatment. 15:396-398 |
| ISSN: | 1471-1753 0954-6634 |
| DOI: | 10.1080/09546630410022440 |
| Popis: | A 47-year-old woman presented with erythematous lesions with papules and pustules on her parieto-occipital region that had been present for 8 months. Areas of sclero-atrophic alopecia were evident, whereas at different points tufted hair shafts were coming out from single dilatated follicular ostia. Before our observation, an antibiotic oral therapy with tetracyclines and local with erythromycin had been administered to the patient, with partial improvement and relapse on its suspension.Bacterial culture from pustules showed the development of Staphylococcus aureus. A skin biopsy was done. According to clinical and histopathological findings a diagnosis of tufted hair folliculitis was made and a treatment with oral rifampicin was started at the dosage of 450 mg twice per day.After 3 weeks of therapy, the pustular lesions regressed completely and after a follow-up of 1 year no relapse was observed.Rifampicin is one of the best active antibiotics against S. aureus, which seems to play a role in the pathogenesis of tufted hair folliculitis. Our results, if further confirmed, may suggest a role for rifampicin either for the control of the pustular phase of this rare disorder or to prevent its relapses for a long time. |
| Databáze: | OpenAIRE |
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