Macrophages in Collateral Arteriogenesis
Autor: | Erik Fung, Armin Helisch |
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Rok vydání: | 2012 |
Předmět: |
Pathology
medicine.medical_specialty collateral artery Necrosis Physiology Collateral Adverse outcomes Angiogenesis growth Review Article 030204 cardiovascular system & hematology lcsh:Physiology angiogenesis 03 medical and health sciences 0302 clinical medicine vascular Physiology (medical) medicine remodeling 030304 developmental biology 0303 health sciences lcsh:QP1-981 Vascular disease business.industry medicine.disease macrophages 3. Good health medicine.anatomical_structure arteriogenesis Arteriogenesis medicine.symptom monocytes business Perfusion Artery |
Zdroj: | Frontiers in Physiology Frontiers in Physiology, Vol 3 (2012) |
ISSN: | 1664-042X |
Popis: | Arteriosclerotic vascular disease is the most common cause of death and a major cause of disability in the developed world. Adverse outcomes of arteriosclerotic vascular disease are related to consequences of tissue ischemia and necrosis affecting the heart, brain, limbs, and other organs. Collateral artery growth or arteriogenesis occurs naturally and can help restore perfusion to ischemic tissues. Understanding the mechanisms of collateral artery growth may provide therapeutic options for patients with ischemic vascular disease. In this review, we examine the evidence for a role of monocytes and macrophages in collateral arteriogenesis. |
Databáze: | OpenAIRE |
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