Time Trends in the Use of Coronary Procedures, Guideline-Based Therapy, and All-Cause Mortality following the Acute Coronary Syndrome in Patients with Schizophrenia
| Autor: | Rene Ernst Nielsen, Rubina Attar, Svend Eggert Jensen, Kristian Kragholm, Christoffer Polcwiartek, Christian Torp Pedersen, Pontus Andell |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Acute coronary syndrome medicine.medical_specialty medicine.medical_treatment Denmark Population Comorbidity Coronary Angiography behavioral disciplines and activities Risk Assessment 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Risk Factors Internal medicine Cause of Death Epidemiology medicine Prevalence Humans Pharmacology (medical) Myocardial infarction Registries Acute Coronary Syndrome education Stroke Aged education.field_of_study business.industry Percutaneous coronary intervention Guideline Middle Aged medicine.disease 030227 psychiatry Case-Control Studies Schizophrenia Female Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Diagnosis of schizophrenia Follow-Up Studies |
| Zdroj: | Attar, R, Jensen, S E, Nielsen, R E, Polcwiartek, C, Andell, P, Pedersen, C T & Kragholm, K 2020, ' Time Trends in the Use of Coronary Procedures, Guideline-Based Therapy, and All-Cause Mortality following the Acute Coronary Syndrome in Patients with Schizophrenia ', Cardiology, vol. 145, no. 7, pp. 401-409 . https://doi.org/10.1159/000507044 |
| ISSN: | 1421-9751 |
| DOI: | 10.1159/000507044 |
| Popis: | Aim: Schizophrenia is associated with high cardiovascular mortality predominantly as a result of acute coronary syndrome (ACS). The aim of this study is to analyze time trends of coronary procedures, guideline-based therapy, and all-cause mortality in patients diagnosed with schizophrenia. Methods and Results: This Danish nationwide register-based study analyzed 734 patients with a baseline diagnosis of schizophrenia and an incident diagnosis of ACS in the period between January 1, 1996, and December 31, 2015. The 734 patients with schizophrenia were matched to 2,202 psychiatric healthy controls (PHC). No change over time was seen in the relative difference between the population with schizophrenia and the PHC in the use of coronary angiography, percutaneous coronary intervention, and coronary bypass grafting, nor in 1-year mortality or guideline-based therapy following ACS. Patients with schizophrenia had higher prevalence rates of diabetes, chronic obstructive pulmonary disease, and stroke, and a lower prevalence of hypertension (p < 0.05). Conclusion: The gap in the use of coronary procedures, guideline-based therapy, and all-cause mortality following ACS in patients with schizophrenia compared to those without has remained constant over the past 2 decades. |
| Databáze: | OpenAIRE |
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