Evaluation of the peritoneal equilibration test in children on chronic peritoneal dialysis
| Autor: | B. Damiani, S. Guez, Marina Picca, Alberto Edefonti, Marisa Giani, Luciana Ghio, A Dal Col, C Santeramo, R. Galato |
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| Předmět: |
Chronic peritoneal dialysis
medicine.medical_specialty business.industry medicine.medical_treatment Ultrafiltration General Medicine Peritoneal equilibration test Surgery Peritoneal dialysis Investigation methods medicine.anatomical_structure Peritoneum Nephrology medicine Peritoneal transport rate Dialisis peritoneal business |
| Zdroj: | ResearcherID |
| Popis: | The peritoneal equilibration test (PET) is routinely performed in adults treated with chronic peritoneal dialysis to assess the peritoneal transport rate and to optimize treatment prescription. Only a few and not well-standardized studies on the PET have been reported in children. Twenty-six PETs were performed In 16 children, mean age 10.9±4.9 years, mean body weight (BW) 26.8±11.9 kg, treated with nightly intermittent peritoneal dialysis (NIPD). The PET was performed according to Twardowski. Forty mL/kg BW of 2.27% glucose solution were Infused at a rate of 10 mL/kg BW every 2 minutes. In the simplified test, dialysate samples were taken at dwell times 0, 2 and 4 hours for glucose and creatinine. A blood sample was taken after a 2-hour dwell time for the same parameters. The standard PET (8 patients) consisted of dialysate samples at 0, 15, 30, 60, 120, and 240 minutes and blood samples at 0 and 240 minutes. Mean DIP ratio for corrected creatinine and DIDo ratio for glucose at 2 hours were 51.6±11.6 and 50.4±9, respectively; at 4 hours 69.6± 12 and 34.4±9.8, respectively. There was good correlation between DIP creatinine and DIDo glucose at 4 hours (p In conclusion, the PET, modified for use in children, gave reliable and reproducible results. Mean values of DIP creatinine for children were higher and DIDo glucose lower than those of adults as reported by Twardowskl. A consistent percentage of children had, nevertheless, a low-average or low transport rate. Standard PET is required in case of automated peritoneal dialysis prescription. |
| Databáze: | OpenAIRE |
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