European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten‐related disorders

Autor: David S Sanders, Chris J. J. Mulder, Umberto Volta, Renata Auricchio, Knut E.A. Lundin, Gemma Castillejo, Abdulbaqi Al-toma, Christophe Cellier
Přispěvatelé: Al-Toma, Abdulbaqi, Volta, Umberto, Auricchio, Renata, Castillejo, Gemma, Sanders, David S, Cellier, Christophe, Mulder, Chris J, Lundin, Knut E A
Rok vydání: 2019
Předmět:
Adult
medicine.medical_specialty
Dermatitis Herpetiformis
enteropathy associated T-cell lymphoma
Coeliac disease
Serology
Diet
Gluten-Free
03 medical and health sciences
0302 clinical medicine
Dermatitis herpetiformis
dermatitis herpetiformi
Biopsy
refractory coeliac disease
medicine
Humans
coeliac neuropathy
Child
Letters to the Editor
Dietary Supplement
chemistry.chemical_classification
medicine.diagnostic_test
non-coeliac gluten sensitivity
business.industry
neurocoeliac
seronegative coeliac disease
Gastroenterology
nutritional and metabolic diseases
Guideline
medicine.disease
Dermatology
Gluten
digestive system diseases
Clinical trial
slow-responder coeliac
Celiac Disease
Oncology
chemistry
030220 oncology & carcinogenesis
Dietary Supplements
Quality of Life
Enteropathy-associated T-cell lymphoma
030211 gastroenterology & hepatology
Immunotherapy
business
gluten ataxia
Human
Zdroj: European Journal of Gastroenterology & Hepatology
Al-Toma, A, Volta, U, Auricchio, R, Castillejo, G, Sanders, D S, Cellier, C, Mulder, C J & Lundin, K E A 2019, ' European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders ', United European Gastroenterology Journal, vol. 7, no. 5, pp. 583-613 . https://doi.org/10.1177/2050640619844125
ISSN: 2050-6414
2050-6406
Popis: This guideline presents recommendations for the management of coeliac disease (CD) and other gluten-related disorders both in adults and children. There has been a substantial increase in the prevalence of CD over the last 50 years and many patients remain undiagnosed. Diagnostic testing, including serology and biopsy, should be performed on a gluten-containing diet. The diagnosis of CD is based on a combination of clinical, serological and histopathological data. In a group of children the diagnosis may be made without biopsy if strict criteria are available. The treatment for CD is primarily a gluten-free diet (GFD), which requires significant patient education, motivation and follow-up. Slow-responsiveness occurs frequently, particularly in those diagnosed in adulthood. Persistent or recurring symptoms necessitate a review of the original diagnosis, exclude alternative diagnoses, confirm dietary adherence (dietary review and serology) and follow-up biopsy. In addition, evaluation to exclude complications of CD, such as refractory CD or lymphoma, should be performed. The guideline also deals with other gluten-related disorders, such as dermatitis herpetiformis, which is a cutaneous manifestation of CD characterized by granular IgA deposits in the dermal papillae. The skin lesions clear with gluten withdrawal. Also, less well-defined conditions such as non-coeliac gluten sensitivity (NCGS) and gluten-sensitive neurological manifestations, such as ataxia, have been addressed. Newer therapeutic modalities for CD are being studied in clinical trials but are not yet approved for use in practice.
Databáze: OpenAIRE
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