Acid-soluble precursors and derivatives of phospholipids increase after stimulation of quiescent swiss 3T3 mouse fibroblasts with serum
| Autor: | Craig H Warden, Morris Friedkin, Paul J. Geiger |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Biophysics
Phospholipid Stimulation Biology Biochemistry Phosphates Mice chemistry.chemical_compound Adenosine Triphosphate Fructosediphosphates Animals Growth Substances Molecular Biology Cells Cultured Phospholipids Phosphocholine Transition (genetics) Nucleotides Phosphatidylethanolamines Cell Cycle DNA replication Fructose Cell Biology Phosphate Glycerylphosphorylcholine Solubility chemistry Fetal bovine serum |
| Zdroj: | Biochemical and Biophysical Research Communications. 94:690-696 |
| ISSN: | 0006-291X |
| Popis: | Automated phosphate analysis of acid-soluble pools of phosphate esters was employed to reveal possible biochemical changes during the transition of Swiss 3T3 mouse fibroblasts from quiescence to active replication of DNA. After 12 hours of stimulation with 10% fetal bovine serum the most notable were 3-fold increases in pools of phospholipid precursors and derivatives. These included glycerophosphocholine, glycerophosphoethanolamine, phosphocholine and phosphoethanolamine. Concurrent but less dramatic increases in pools of ATP, CTP and fructose 1,6-diphosphate were also obtained. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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