Usefulness of apparent diffusion coefficient of diffusion-weighted imaging for differential diagnosis of primary solid and cystic renal masses
| Autor: | Serap Doğan, Mehmet Öztürk, Şenol Fatih Elbir, Afra Ekinci, Aylin Okur, Okkes Ibrahim Karahan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Diagnostic methods carcinoma 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Carcinoma Cutoff Effective diffusion coefficient magnetic resonance imaging Carcinoma Renal Cell diffusion magnetic resonance imaging medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging renal cell Anesthesiology and Pain Medicine Diffusion Magnetic Resonance Imaging 030220 oncology & carcinogenesis Original Article Radiology Differential diagnosis business Diffusion MRI |
| Zdroj: | Polish Journal of Radiology |
| Popis: | Summary Background To evaluate the value of diffusion-weighted imaging (DWI) for distinguishing between benign and malignant renal masses. Material/Methods Seventy-five patients with 75 unilateral renal lesions were included, and 75 normal contralateral kidneys served as controls. The lesions were categorized into four groups as malignant cystic, malignant solid, benign cystic and benign solid. The apparent diffusion coefficients (ADCs) were evaluated for two different b values (b=600 s/mm2 and b=1000 s/mm2). Receiving operating characteristic analysis was performed to identify threshold ADCs. Results Sensitivity and specificity were 67% and 77% (p=0.003) at the cutoff value of 1.5 for b=600 s/mm2, and 79% and 62% (p=0.004) at the cutoff value of 1.99 for b=1000 s/mm2 as regards the differentiation between solid benign and malignant renal lesions. Sensitivity and specificity were 78% and 79% (p=0.001) at the cutoff value of 3.1 for b=600 s/mm2, and 86% and 61% (p=0.003) at the cutoff value of 2.9 for b=1000 s/mm2 as regrads the differentiation between benign and malignant cystic renal lesions. Conclusions DWI can be an effective diagnostic method for distinguishing between benign and malignant renal masses. |
| Databáze: | OpenAIRE |
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