Use of biological model of isolated overloading of skeletal muscle for determination of anabolic effect of steranobols
| Autor: | S. N. Almaeva, E. E. Belen'kii, V. P. Fedotov, T. I. Ivanenko |
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| Rok vydání: | 1980 |
| Předmět: |
Male
medicine.medical_specialty Anabolism Anabolic Effect Models Biological chemistry.chemical_compound Anabolic Agents Internal medicine medicine Animals Nandrolone Dose-Response Relationship Drug Biological modeling Muscles General Neuroscience Skeletal muscle Organ Size Rats Tendon Endocrinology Levator ani medicine.anatomical_structure Castration chemistry Nandrolone Decanoate Muscle Contraction |
| Zdroj: | Neuroscience and Behavioral Physiology. 10:223-227 |
| ISSN: | 1573-899X 0097-0549 |
| DOI: | 10.1007/bf01182215 |
| Popis: | 1. A model for determining the anabolic effect of long-acting steroid preparations, which consists of isolated overloading of the skeletal muscles of the orus, m. soleus and m. plantaris, after sectioning of the tendon of m. gastrocnemius, was tested. 2. The method permits the use of animals of different weight, age, and sex, without castration. 3. A comparative study of the anabolic properties of a preparation of retabolyl using the proposed biological model and the generally accepted method of testing according to the change in the mass of m. levator ani showed that the model of an isolated overload can be used for a quantitative evaluation of the actual anabolic effect as a rather simple, sensitive, and informative method. |
| Databáze: | OpenAIRE |
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