Patients with Multiple Hepatocellular Carcinomas Within the UCSF Criteria Have Outcomes After Curative Resection Similar to Patients Within the BCLC Early-Stage Criteria
| Autor: | Guang-Shun Yang, Wen-Chao Zhao, Hua-Bang Zhou, Nan Zhu, Ben-Dong Chen, Yong Fu, Wen-Ke Cai, Ning Yang, Haibin Zhang |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Surgical margin medicine.medical_specialty Carcinoma Hepatocellular education Gastroenterology Neoplasms Multiple Primary Liver Function Tests Predictive Value of Tests Risk Factors Internal medicine Biomarkers Tumor medicine Carcinoma Humans Stage (cooking) Survival rate Aged Neoplasm Staging Proportional Hazards Models Chi-Square Distribution Proportional hazards model business.industry Liver Neoplasms Middle Aged Prognosis medicine.disease Survival Rate Treatment Outcome Predictive value of tests Female Surgery Liver cancer business Chi-squared distribution |
| Zdroj: | World Journal of Surgery. 36:1811-1823 |
| ISSN: | 1432-2323 0364-2313 |
| Popis: | Surgical strategies for the treatment of multiple hepatocellular carcinomas (HCC) remain controversial. This study compared the prognostic power of the University of California, San Francisco (UCSF) criteria with the Barcelona Clinic Liver Cancer (BCLC) early-stage criteria. Clinical and survival data of 162 multiple-HCC patients in Child-Pugh class A who underwent curative resection were retrospectively reviewed. Prognostic risk factors were analyzed using univariate and multivariate analyses. UCSF criteria were shown to independently predict overall and disease-free survival. In patients within the UCSF criteria, 3-year overall and disease-free survivals were significantly better than in those exceeding the UCSF criteria (68 vs. 34 % and 54 vs. 26 %, respectively; both p |
| Databáze: | OpenAIRE |
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