The Zebrafish Information Network: new support for non-coding genes, richer Gene Ontology annotations and the Alliance of Genome Resources
| Autor: | Ryan Martin, Sabrina Toro, Holly Paddock, Anne E. Eagle, Patrick Kalita, Monte Westerfield, Yvonne M. Bradford, David Fashena, Xiang Shao, Christian Pich, Prita Mani, Sierra A. T. Moxon, Sridhar Ramachandran, Douglas G. Howe, Ceri E. Van Slyke, Kevin Schaper, Ken Frazer, Amy Singer, Leyla Ruzicka |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
animal structures
ved/biology.organism_classification_rank.species Mutant Gene Expression Computational biology Biology Genome 03 medical and health sciences 0302 clinical medicine Databases Genetic Genetics Database Issue Animals Humans Model organism Genome Reference Consortium Gene Zebrafish 030304 developmental biology 0303 health sciences ved/biology Molecular Sequence Annotation Genomics biology.organism_classification Phenotype Gene Ontology Mutation Zebrafish Information Network genome database 030217 neurology & neurosurgery |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 0305-1048 |
| Popis: | The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for the model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a wide array of zebrafish genetic and genomic data, including genes, alleles, transgenic lines, gene expression, gene function, mutant phenotypes, orthology, human disease models, nomenclature and reagents. New features at ZFIN include increased support for genomic regions and for non-coding genes, and support for more expressive Gene Ontology annotations. ZFIN has recently taken over maintenance of the zebrafish reference genome sequence as part of the Genome Reference Consortium. ZFIN is also a founding member of the Alliance of Genome Resources, a collaboration of six model organism databases (MODs) and the Gene Ontology Consortium (GO). The recently launched Alliance portal (https://alliancegenome.org) provides a unified, comparative view of MOD, GO, and human data, and facilitates foundational and translational biomedical research. |
| Databáze: | OpenAIRE |
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