Thymosin fraction 5 stimulates the release of prolactin from cultured GH3 cells
| Autor: | Allan L. Goldstein, Bryan L. Spangelo, Adrian J. Dunn, Nicholas R. Hall |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
endocrine system
medicine.medical_specialty Pituitary gland Dose-Response Relationship Drug Thymosin Stimulation Thymus Gland General Medicine Biology General Biochemistry Genetics and Molecular Biology Prolactin medicine.anatomical_structure Endocrinology Pituitary Gland Anterior Cell culture Internal medicine medicine Endocrine system Secretion General Pharmacology Toxicology and Pharmaceutics hormones hormone substitutes and hormone antagonists Function (biology) |
| Zdroj: | Life Sciences. 40:283-288 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(87)90344-4 |
| Popis: | Thymosin fraction 5, a bovine thymus preparation, has recently been implicated in the regulation of neuroendocrine function. The purpose of the present study was to investigate the effects of thymosin fraction 5 treatment upon the GH3 rat pituitary cell line. Thymosin fraction 5 stimulated prolactin (PRL) release from these cells in a dose and time dependent manner. These results suggest that a product of the endocrine thymus may regulate the release of PRL. |
| Databáze: | OpenAIRE |
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