The Circadian Clock, the Brain, and COVID-19: The Cases of Olfaction and the Timing of Sleep
| Autor: | Rachel S. Herz, Martha Merrow, Erik D. Herzog, Sara B Noya |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Physiology
Circadian clock Review Olfaction Circadian Clocks Physiology (medical) Animals Humans Medicine Circadian rhythm sleep Wakefulness neurological SARS-CoV-2 business.industry COVID-19 Brain Cognition Human brain Neurophysiology Sleep in non-human animals Circadian Rhythm Smell circadian medicine.anatomical_structure business Neuroscience olfaction |
| Zdroj: | Journal of Biological Rhythms |
| ISSN: | 1552-4531 0748-7304 |
| DOI: | 10.1177/07487304211031206 |
| Popis: | Daily rhythms of behavior and neurophysiology are integral to the circadian clocks of all animals. Examples of circadian clock regulation in the human brain include daily rhythms in sleep-wake, cognitive function, olfactory sensitivity, and risk for ischemic stroke, all of which overlap with symptoms displayed by many COVID-19 patients. Motivated by the relatively unexplored, yet pervasive, overlap between circadian functions and COVID-19 neurological symptoms, this perspective piece uses daily variations in the sense of smell and the timing of sleep and wakefulness as illustrative examples. We propose that time-stamping clinical data and testing may expand and refine diagnosis and treatment of COVID-19. |
| Databáze: | OpenAIRE |
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