Iodine, a Mild Reagent for the Aromatization of Terpenoids
| Autor: | José F. Quílez del Moral, Lúcia Silva, Consuelo Prieto, Alejandro F. Barrero, Jesus M. Rodilla, Victoriano Domingo |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Diene
Propanols Pharmaceutical Science chemistry.chemical_element 010402 general chemistry Iodine 01 natural sciences Analytical Chemistry chemistry.chemical_compound Drug Discovery Humans Organic chemistry Testosterone Dehydrogenation Pharmacology Molecular Structure Terpenes 010405 organic chemistry Chemistry Organic Chemistry Aromatization Allylic alcohol Terpenoid 0104 chemical sciences Complementary and alternative medicine Reagent Molecular Medicine |
| Zdroj: | Journal of Natural Products. 79:831-837 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/acs.jnatprod.5b00914 |
| Popis: | Efficient procedures based on the use of iodine for the aromatization of a series of terpenoids possessing diene and homoallylic or allylic alcohol functionalities are described. Different examples are reported as a proof-of-concept study. Furthermore, iodine also proved to mediate the dehydrogenation of testosterone. |
| Databáze: | OpenAIRE |
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