Postprandial leukocyte increase in healthy subjects
| Autor: | B. S. Van Asbeck, A.J.H.H.M. van Oostrom, Ton J. Rabelink, T.P. Sijmonsma, M. Castro Cabezas |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutrophils Endocrinology Diabetes and Metabolism Pathogenesis chemistry.chemical_compound Leukocyte Count Endocrinology Oral administration Reference Values Internal medicine medicine Ingestion Humans Meal Triglyceride business.industry Hypertriglyceridemia medicine.disease Postprandial Period Dietary Fats Postprandial chemistry business Body mass index Cell Division |
| Zdroj: | Metabolism: clinical and experimental. 52(2) |
| ISSN: | 0026-0495 |
| Popis: | Atherosclerosis is an inflammatory disorder involving leukocytes and lipids. To study the relationship between leukocytes and lipids in vivo, leukocyte changes were determined in 14 healthy males (age, 23 ± 3 years; body mass index [BMI], 21.9 ± 1.5 kg/m2) after an 8-hour oral fat load (50 g/m2) and after water. The postprandial triglyceride (TG) increment after fat was paralleled by a leukocyte increment, due to an increase in neutrophils in the first 2 hours (142% ± 69% higher than baseline, P =.04). Neutrophil counts did not return to baseline at the end of the test. Water ingestion did not induce significant neutrophil changes. Blood lymphocytes increased gradually in both tests (142% ± 30% higher than baseline, P |
| Databáze: | OpenAIRE |
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