Mycophenolate mofetil in pediatric renal transplantation
| Autor: | Naser Simfroosh, Mostafa Sharifian, N. Sedigh, H Otukesh, Mahdi Rezai, Rozita Hoseini, Pedram Golnari, M. Fereshtenejad, Abbas Basiri |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Graft Rejection
medicine.medical_specialty Urinary system Urology Renal function Azathioprine Mycophenolic acid medicine Humans Child Kidney transplantation Retrospective Studies Transplantation Kidney business.industry Graft Survival Mycophenolic Acid medicine.disease Kidney Transplantation Surgery surgical procedures operative medicine.anatomical_structure Chronic Disease Prednisolone business Immunosuppressive Agents medicine.drug |
| Zdroj: | Transplantation proceedings. 37(7) |
| ISSN: | 0041-1345 |
| Popis: | Introduction. Since kidney transplantation is the therapy of choice for children with end-stage renal disease (ESRD), we investigated the effects of mycophenolate mofetil (MMF) in pediatric renal transplantation. Methods and subjects. Two hundred sixteen children received renal transplants between 1985 and 2003: 100 patients received MMF with cyclosporine and prednisolone (cases), and 116 patients, azathioprine with cyclosporine and prednisolone (controls). Results. The MMF group (100 patients) showed better graft survival and function than the AZA group (116 patients). Patients who received MMF immediately after transplantation experienced less graft loss and acute rejection episodes in the first 3 months after transplantation (P |
| Databáze: | OpenAIRE |
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