Nanotechnology, Nanomedicine, and the Kidney
Autor: | Morgan Hamon, Hsiao-Min Chang, Peter Hauser, Norimoto Yanagawa |
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Rok vydání: | 2021 |
Předmět: |
Drug
kidney Technology QH301-705.5 Fluid homeostasis QC1-999 media_common.quotation_subject 02 engineering and technology Bioinformatics 01 natural sciences renal imaging medicine General Materials Science Biology (General) QD1-999 Instrumentation media_common Fluid Flow and Transfer Processes Kidney nanotechnology 010405 organic chemistry business.industry nanoparticle Physics Process Chemistry and Technology General Engineering Engineering (General). Civil engineering (General) 021001 nanoscience & nanotechnology nanomedicine 0104 chemical sciences Computer Science Applications Chemistry medicine.anatomical_structure Renal imaging tissue engineering Renal physiology Drug delivery Nanomedicine TA1-2040 0210 nano-technology business Clearance |
Zdroj: | Applied Sciences, Vol 11, Iss 7187, p 7187 (2021) |
ISSN: | 2076-3417 |
Popis: | The kidneys are vital organs performing several essential functions. Their primary function is the filtration of blood and the removal of metabolic waste products as well as fluid homeostasis. Renal filtration is the main pathway for drug removal, highlighting the importance of this organ to the growing field of nanomedicine. The kidneys (i) have a key role in the transport and clearance of nanoparticles (NPs), (ii) are exposed to potential NPs’ toxicity, and (iii) are the targets of diseases that nanomedicine can study, detect, and treat. In this review, we aim to summarize the latest research on kidney-nanoparticle interaction. We first give a brief overview of the kidney’s anatomy and renal filtration, describe how nanoparticle characteristics influence their renal clearance, and the approaches taken to image and treat the kidney, including drug delivery and tissue engineering. Finally, we discuss the future and some of the challenges faced by nanomedicine. |
Databáze: | OpenAIRE |
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