Heavy metal bioaccumulation and histopathological alterations in wild Arctic hares (Lepus arcticus) inhabiting a former lead-zinc mine in the Canadian high Arctic: A preliminary study
| Autor: | J. Attitaq, M. Amuno, Som Niyogi, S. Amuno |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Canada medicine.medical_specialty Environmental Engineering Zoology 010501 environmental sciences Biology 01 natural sciences Mining Metal 03 medical and health sciences Metals Heavy Lead zinc medicine Animals Soil Pollutants Environmental Chemistry Trace metal Waste Management and Disposal 0105 earth and related environmental sciences Kidney Arctic Regions Ecology Heavy metals Hares Pollution Zinc 030104 developmental biology medicine.anatomical_structure Lead Arctic visual_art Bioaccumulation visual_art.visual_art_medium Histopathology Environmental Monitoring |
| Zdroj: | Science of The Total Environment. 556:252-263 |
| ISSN: | 0048-9697 |
| DOI: | 10.1016/j.scitotenv.2016.03.007 |
| Popis: | A preliminary study was undertaken to determine post-mining baseline accumulation of selected trace metals, and histopathological alterations in free-living arctic hares (Lepus arcticus) inhabiting the vicinity of a former lead-zinc mine located on North Baffin Island in the Canadian High Arctic. Trace metal analysis included measurement of As, Cd, Fe, Pb and Zn in tissues, and histopathological assessment comprised of evaluation and scoring the severity of metal-induced hepatic and renal lesions. Metal contents in hepatic and renal tissues from hares from the mine area compared with the reference locations did not differ significantly suggesting that the animals are not uniformly exposed to background levels of metals in the environment. However, relatively higher accumulation pattern of Pb and Cd were noted in liver tissues of hare from the mine area compared to the background area, but did not induce increased lesions. Surface soils near the mine area contained relatively higher levels of trace metals (Zn>Mn>Pb>Cd>As) compared to reference soils, and with soil levels of Cd showing strong correlation with Cd accumulation in kidney tissues. Generally, both case and reference animals showed similar but varying severities of hepatic and renal lesions at the sublethal level, notably vascular congestion, occasional large hepatocyte nuclei, binucleate hepatocytes, yellow-brown pigmentation in the cytoplasm of hepatocytes and clustering of lymphocytes. Only hares with relatively higher accumulation of Pb from the mine area showed evidence of renal edema and hemorrhage of the capsular surface. This study constitutes the first assessment of metal induced histopathological alterations in arctic hares exposed to a historical mining area in the high arctic. |
| Databáze: | OpenAIRE |
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