Effects of exercise rehabilitation training on patients with pulmonary hypertension
| Autor: | Xiaojun Zhang, Danyan Xu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Elevated pulmonary artery pressure exercise rehabilitation training Review Article 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Right heart failure Quality of life pulmonary hypertension medicine lcsh:RC705-779 business.industry lcsh:Diseases of the respiratory system medicine.disease Pulmonary hypertension Clinical trial cardiac rehabilitation 030104 developmental biology medicine.anatomical_structure lcsh:RC666-701 Ventricle Rehabilitation exercise Physical therapy Vascular resistance business |
| Zdroj: | Pulmonary Circulation Pulmonary Circulation, Vol 10 (2020) |
| ISSN: | 2045-8940 2045-8932 |
| Popis: | Pulmonary hypertension (PH) comprises a group of pathophysiological syndromes characterized by elevated pulmonary artery pressure and pulmonary vascular resistance, which lead to right ventricular overload, and even right heart failure. PH has a poor prognosis and severely leads to a decline in quality of life. Historically, patients with PH were advised to limit their physical activity. However, an increasing number of studies have reported the safety and efficacy of exercise rehabilitation training in PH. This review briefly examined and summarized the effects of exercise rehabilitation training on PH patients reported in the recent literature. The findings of the reviewed studies indicate that exercise rehabilitation training in PH patients has beneficial effects in terms of exercise capacity and quality of life, vascular and right ventricle remodelling, inflammatory response, muscular function and oxidative stress. However, the underlying mechanisms and appropriate exercise strategies (e.g. the duration and intensity of exercise) still need to be explored. In conclusion, exercise rehabilitation training of the appropriate intensity and frequency can improve the prognosis and quality of life of PH patients. The training should be monitored by professional staff and be provided as an adjunct to pharmacological treatment. Larger clinical trials are required to confirm the safety and efficacy of exercise rehabilitation training in PH. |
| Databáze: | OpenAIRE |
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