Neurodevelopmental Outcomes of Very Low Birth Weight Infants at 18–24 Months, Corrected Gestational Age in a Tertiary Health Centre: A Prospective Cohort Study
Autor: | Atanu Kumar Jana, Hannah Grace, Rachel Beulah, T O Swathi, Samuel Philip Oommen, Niranjan Thomas, Manish Kumar, Bijesh Yadav, Sridhar Santhanam, Caroline Sanjeev Padankatti, Hima B John, Reeba Roshan |
---|---|
Rok vydání: | 2019 |
Předmět: |
Pediatrics
medicine.medical_specialty Multivariate analysis Hearing loss Developmental Disabilities Visual impairment India Gestational Age Cerebral palsy 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics Prevalence medicine Humans Infant Very Low Birth Weight Hospitals Teaching Prospective cohort study Psychological Tests business.industry Infant Gestational age medicine.disease Low birth weight Infectious Diseases Pediatrics Perinatology and Child Health Cohort medicine.symptom business Infant Premature Psychomotor Performance 030217 neurology & neurosurgery Follow-Up Studies |
Zdroj: | Journal of Tropical Pediatrics. 65:552-560 |
ISSN: | 1465-3664 |
DOI: | 10.1093/tropej/fmz006 |
Popis: | Objective To determine the prevalence and risk factors for poor neurodevelopmental outcome in a cohort of very low birth weight (VLBW) infants. Subjects and methods Four hundred and twenty-two infants of a total of 643 VLBW survivors from a teaching hospital in South India were followed up to assess their neurodevelopmental outcomes. Results Among the 422 children who completed the assessment, results of 359 children whose assessments were done between 18 and 24 months were analysed. Thirty-seven children (10.31%) had poor neurodevelopmental outcome, six children [1.67%] had cerebral palsy, one child had visual impairment and another had hearing impairment. Poor post-natal growth was independently associated with poor neurodevelopmental outcomes in the multivariate analysis (p = 0.045). Neonatal complications were not associated with the developmental outcome. Conclusion Despite lower rates of neonatal complications compared with Western cohorts, significant proportion of VLBW infants had poor neurodevelopmental outcomes. Poor post-natal growth was an important determinant of the developmental outcome |
Databáze: | OpenAIRE |
Externí odkaz: |