A biosensor for the detection of single base mismatches in microRNA
| Autor: | Dal-Hee Min, Ginam Park, Jieon Lee |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Peptide nucleic acid
Chemistry Graphene Base Pair Mismatch Metals and Alloys Analytical chemistry RNA General Chemistry Biosensing Techniques Fluorescence Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials law.invention chemistry.chemical_compound MicroRNAs Spectrometry Fluorescence law Duplex (building) microRNA Materials Chemistry Ceramics and Composites Biophysics Biosensor |
| Zdroj: | Chemical communications (Cambridge, England). 51(78) |
| ISSN: | 1364-548X |
| Popis: | Graphene oxide quenches fluorescence corresponding to only a mismatched target due to selective denaturing of the thermo-unstable duplex composed of probe peptide nucleic acid and single base mismatched target RNA and thus, the fluorescence signal only from perfectly matched target RNA is measured. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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