Per-protocol effect of earlier non-pneumatic anti-shock garment application for obstetric hemorrhage
| Autor: | Eduardo Bergel, Mario Merialdi, Christine Kaseba, Luz Gibbons, Suellen Miller, Elizabeth Butrick, Gricelia Mkumba, Thulani Magwali, Alison M. El Ayadi, N. T. My Huong |
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| Rok vydání: | 2013 |
| Předmět: |
Maternal mortality
Zimbabwe medicine.medical_specialty Obstetric hemorrhage Time Factors Referral Adverse outcomes Zambia Intervention effect Article Clothing Paediatrics and Reproductive Medicine Clinical Protocols Pregnancy Primary health medicine First Aid Humans Intensive care medicine Obstetrics & Reproductive Medicine business.industry NASG Postpartum Hemorrhage Hypovolemic shock Obstetrics and Gynecology General Medicine medicine.disease Good Health and Well Being Shock (circulatory) Emergency medicine Non-pneumatic anti-shock garment Female medicine.symptom business First aid Maternal morbidity |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol 126, iss 1 |
| ISSN: | 1879-3479 |
| Popis: | Obstetric hemorrhage is the primary cause of maternal mortality worldwide, especially in lower-resource settings that are characterized by treatment delays [1]. The non-pneumatic anti-shock garment (NASG) is a first-aid device used to stabilize women in shock from obstetric hemorrhage until they can receive definitive care. The authors conducted a cluster-randomized trial (CRT) to evaluate NASG application at the primary health clinic prior to referral hospital transfer on maternal outcomes. Control participants received the NASG upon arrival at the referral hospital. The intent-to-treat analysis (ITT) reported a non-statistically significant 46% reduction in mortality, 54% reduction in extreme adverse outcomes, and a significant 25% faster recovery from shock associated with earlier NASG intervention [2]. However, protocol violations occurred, potentially diluting the intervention effect. Thus, the effect of earlier NASG application was evaluated using 2 per-protocol analysis strategies. |
| Databáze: | OpenAIRE |
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