Rapid analysis of biogenic amines from rice wine with isotope-coded derivatization followed by high performance liquid chromatography–tandem mass spectrometry
| Autor: | Caiqing Zhang, Zhiwei Sun, Xiaomei Liu, Guang Chen, Yiping Cai, Jinmao You |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Biogenic Amines
Wine Mass spectrometry Tandem mass spectrometry 01 natural sciences Chloride High-performance liquid chromatography Analytical Chemistry chemistry.chemical_compound 0404 agricultural biotechnology Tandem Mass Spectrometry medicine Derivatization Chromatography High Pressure Liquid Chromatography Isotope 010401 analytical chemistry Oryza 04 agricultural and veterinary sciences General Medicine 040401 food science 0104 chemical sciences chemistry Reagent Food Science medicine.drug |
| Zdroj: | Food Chemistry. 192:388-394 |
| ISSN: | 0308-8146 |
| Popis: | A pair of isotope-coded derivatization reagents, d0-10-methyl-acridone-2-sulfonyl chloride (d0-MASC, light form) and d3-10-methyl-acridone-2-sulfonyl chloride (d3-MASC, heavy form), were used for labeling biogenic amines (BAs). On basis of the isotope-coded derivatization, a global isotope internal standard quantitative method for determining seven BAs by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed. The d0-MASC and d3-MASC can easily label BAs under mild conditions within 15 min at 50 °C. The obtained light and heavy labeled BAs were monitored by the transitions of [M+H](+) → 208 and [M+H](+) → 211, respectively. Relative quantification of BAs was achieved by calculation of the peak area ratios of d0-MASC/d3-MASC labeled derivatives. Excellent linear responses for relative quantification were observed in the range of 1/10-10/1. The developed method has been successfully applied to the quantification of BAs in Chinese rice wine with recoveries ranging from 94.9% to 104.5%. |
| Databáze: | OpenAIRE |
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