CT and MR features of xanthogranulomatous cholecystitis: an analysis of consecutive 49 cases
| Autor: | Pu-Xuan Lu, Gao-Feng Wang, Shi-Zheng Zhang, Yi-Xiang J. Wang, Feng Zhao, Senxiang Yan, Jing Yuan |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Gallbladder wall thickening medicine.medical_specialty Gallbladder Stone Sensitivity and Specificity Abdominal wall medicine Cholecystitis Xanthomatosis Humans Radiology Nuclear Medicine and imaging Xanthogranulomatous Cholecystitis Granuloma business.industry Stomach Gallbladder Reproducibility of Results General Medicine medicine.disease Magnetic Resonance Imaging Cholecystography medicine.anatomical_structure Dual echo Female Radiology business Tomography X-Ray Computed Infiltration (medical) |
| Zdroj: | European journal of radiology. 82(9) |
| ISSN: | 1872-7727 |
| Popis: | Objective To study the CT and MR features of xanthogranulomatous cholecystitis (XGC). Materials and methods 49 patients had pathologically confirmed XGC. All patients underwent contrast enhanced CT, and 10 patients had additional plain MRI. The CT and MRI results were retrospectively analyzed. Results On CT, all patients had thickening of gallbladder wall, with 87.8% cases showed diffuse thickening. 85.7% cases had intramural hypo-attenuated nodules in the thickened wall. Continuous mucosal line and luminal surface enhancement were noted in 79.6% and 85.7% cases, respectively. Gallbladder stones were seen in 69.4% patients. The coexistence of the above 5 CT features was seen in 40% cases, and 80% cases had the coexistence of ≥4 features. Diffused gallbladder wall thickening in XGC is more likely to have disrupted mucosal line, and XGC with disrupted mucosal line is more likely to be associated with liver infiltration. In 60% patients the inflammatory process extended beyond gallbladder, with the interface between gallbladder and liver and/or the surrounding fat blurred. 40% cases had an early enhancement of liver parenchyma. Infiltration to other surrounding tissues included bowel (n = 3), stomach (n = 2), and abdominal wall (n = 1). On MR images, 7 of 9 intramural nodules in 7 subjects with T1-weighted dual echo MR images showed higher signal intensity on in-phase images than out-of-phase images. Conclusion Coexisting of diffuse gallbladder wall thickening, hypo-attenuated intramural nodules, continuous mucosal line, luminal surface enhancement, and gallbladder stone highly suggest XGC. XGC frequently infiltrate liver and surrounding fat. Chemical-shift MRI helps classifying intramural nodules in the gallbladder wall. |
| Databáze: | OpenAIRE |
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