Gender-specific metabolic responses in gonad of mussel Perna viridis to triazophos
| Autor: | Zhang Zhe, Wei Sun, Wengui Cai, Haigang Chen, Linbao Zhang, Jia Xiaoping |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Gonad Perna Hypotaurine 010501 environmental sciences Aquatic Science Biology Oceanography 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Internal medicine Botany medicine Animals Metabolomics Pesticides Gonads Shellfish 0105 earth and related environmental sciences Organophosphate Organothiophosphates Mussel Triazoles biology.organism_classification Pollution 030104 developmental biology medicine.anatomical_structure Endocrinology chemistry Bioaccumulation Female Reproductive toxicity Water Pollutants Chemical Perna viridis |
| Zdroj: | Marine pollution bulletin. 123(1-2) |
| ISSN: | 1879-3363 |
| Popis: | Triazophos, as a lipophilic organophosphate pesticide, displays higher bioaccumulation in the gonads of shellfish. To study the reproductive toxicity of triazophos, we applied metabolomics to characterize the gender-specific metabolic responses in mussel Perna viridis exposed to triazophos. Metabolites were differently altered by triazophos in ovaries of mussel at different concentrations and time intervals, while basically similar metabolic response patterns were observed in male mussels at the two tested concentrations after exposure for 24 and 48 h. The significant changes of metabolites in ovaries of mussel exhibited the disturbances in energy metabolism and osmotic regulation, while in male samples triazophos only affected the energy metabolism. Moreover, glycine, sn-glycero-3-phosphocholine, ethanol, aspartate, etc. exhibited consistent variation tendency in both male and female individuals. While the changes of homarine, betaine, taurine, hypotaurine, malonate, β-alanine, succinate, and choline showed obviously gender-specific responses. Overall, this study confirmed the gender-specific responses in gonad of P. viridis to triazophos exposure. |
| Databáze: | OpenAIRE |
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