Novel Allylic Oxidation of alpha-Cedrene to sec-Cedrenol by a Rhodococcus Strain
| Autor: | Mitsuyoshi Okuda, Yoshiaki Fujikura, Hiromi Kubota, Hiroshi Sonohara, Susumu Ito, Shigeyoshi Tanaka, Hirofumi Takigawa |
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| Rok vydání: | 1993 |
| Předmět: |
Allylic rearrangement
Ecology biology Strain (chemistry) Stereochemistry Cedrene Metabolite biology.organism_classification Physiology and Biotechnology Applied Microbiology and Biotechnology chemistry.chemical_compound chemistry Biochemistry Biotransformation Yield (chemistry) Actinomycetales Rhodococcus Food Science Biotechnology |
| Zdroj: | Applied and environmental microbiology. 59(5) |
| ISSN: | 0099-2240 |
| Popis: | A bacterial strain, designated KSM-7358, that can use α-cedrene for growth was isolated. The strain was identified as a member of the genus Rhodococcus and catalyzed the novel allylic oxidation of α-cedrene regiospecifically to produce ( R )-10-hydroxycedrene ( sec -cedrenol) with a very high yield. α-Curcumene was also produced as a possible metabolite of sec -cedrenol. A possible pathway for the microbial conversion of α-cedrene to sec -cedrenol and α-curcumene is proposed. |
| Databáze: | OpenAIRE |
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