The course of distress in women at increased risk of breast and ovarian cancer due to an (identified) genetic susceptibility who opt for prophylactic mastectomy and/or salpingo-oophorectomy
| Autor: | Caroline Seynaeve, Aad Tibben, Martinus F. Niermeijer, Hugo J. Duivenvoorden, S. van Dooren, A. R. Van Gool, Marian B. E. Menke-Pluijmers, J.G.M. Klijn, A.N. van Geel, Paula J.C. Bresser |
|---|---|
| Přispěvatelé: | Psychiatry, Medical Oncology, Clinical Genetics, Surgery |
| Rok vydání: | 2007 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty medicine.medical_treatment Ovariectomy Breast Neoplasms Anxiety Hospital Anxiety and Depression Scale Genomic disorders and inherited multi-system disorders [IGMD 3] Breast cancer SDG 3 - Good Health and Well-being Avoidance Learning Medicine Humans Genetic Predisposition to Disease Risk factor Fallopian Tubes Mastectomy Molecular diagnosis prognosis and monitoring [UMCN 1.2] Gynecology Ovarian Neoplasms Depressive Disorder business.industry Obstetrics Prophylactic Mastectomy Middle Aged medicine.disease Prophylactic Surgery Distress Oncology Female medicine.symptom business Stress Psychological |
| Zdroj: | European Journal of Cancer, 43, 1, pp. 95-103 European Journal of Cancer, 43, 95-103 European Journal of Cancer, 43(1), 95-103. Elsevier Ltd. |
| ISSN: | 0959-8049 |
| Popis: | Contains fulltext : 52416.pdf (Publisher’s version ) (Closed access) The levels and course of psychological distress before and after prophylactic mastectomy (PM) and/or prophylactic salpingo-oophorectomy (PSO) were studied in a group of 78 women. General distress was measured through the hospital anxiety and depression scale (HADS), cancer-related distress using the impact of events scale (IES). Measurement moments were baseline (2-4 weeks prior to prophylactic surgery), and 6 and 12 months post-surgery. After PM, anxiety and cancer-related distress were significantly reduced, whereas no significant changes in distress scores were observed after PSO. At one year after prophylactic surgery, a substantial amount of women remained at clinically relevant increased levels of cancer-related distress and anxiety. We conclude that most women can undergo PM and/or PSO without developing major emotional distress. More research is needed to further define the characteristics of the women who continue to have clinically relevant increased scores after surgery, in order to offer them additional counselling. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect