Detection of Bronchial Neoplasia in Uranium Miners by Autofluorescence Endoscopy (SAFE-1000)
| Autor: | E. Novotná, J. Pecina, J. Kana, Boris Habanec, V. Vagunda, H. Koukalova, H. Coupková, R. Vrbacky, F. Salajka, Z. Pacovsky, M. Horvathova, T.A Horvath, F. Wurst, Robert Talač, Pavel Pafko, Lenka Foretová |
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| Rok vydání: | 2008 |
| Předmět: |
Pathology
medicine.medical_specialty Intraepithelial neoplasia lcsh:Medical technology medicine.diagnostic_test business.industry H&E stain medicine.disease Endoscopy Autofluorescence Bronchoscopy lcsh:R855-855.5 Dysplasia medicine Bronchial Biopsy Radiology Nuclear Medicine and imaging Histopathology Radiology business Research Article |
| Zdroj: | Diagnostic and Therapeutic Endoscopy Diagnostic and Therapeutic Endoscopy, Vol 5, Iss 2, Pp 91-98 (1999) Scopus-Elsevier |
| ISSN: | 1070-3608 |
| Popis: | The increase in the detection rate for premalignant changes of bronchial epithelium was studied in 56 symptom-free volunteers from the risk group of Czech uranium miners (mean age 50.69 years, mean WLM 21.06 (1 Working Level Month is equal to the absorption of latent energy of 2.08 × 10–5 J/m3 in one month, i.e. 170 working hours)) by the additional employment of the System of Autofluorescence Endoscopy (SAFE-1000 Pentax) to conventional white-light bronchoscopy, comparing results with those of bronchial biopsy histopathology examination. Histopathology using hematoxylin and eosin staining confirmed intraepithelial neoplasias in 15 areas in 10 persons. White-light bronchoscopy sensitivity was 21.05%, and specificity 93.7% which an autofluorescence bronchoscopy sensitivity was 78.95% and specificity 81.89%. |
| Databáze: | OpenAIRE |
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