Molecular Analysis of Blood with Micro-/Nanoscale Field-Effect-Transistor Biosensors

Autor: Matthew S. Makowski, Albena Ivanisevic
Rok vydání: 2011
Předmět:
Zdroj: Small. 7:1863-1875
ISSN: 1613-6810
DOI: 10.1002/smll.201100211
Popis: Rapid and accurate molecular blood analysis is essential for disease diagnosis and management. Field-effect transistor (FET) biosensors are a type of device that promise to advance blood point-of-care testing by offering desirable characteristics such as portability, high sensitivity, brief detection time, low manufacturing cost, multiplexing, and label-free detection. By controlling device parameters, desired FET biosensor performance is obtained. This review focuses on the effects of sensing environment, micro-/nanoscale device structure, operation mode, and surface functionalization on device performance and long-term stability.
Databáze: OpenAIRE