Clinical Depression in Children and Adolescents With Sickle Cell Anaemia: Influencing Factors in a Resource-limited Setting
| Autor: | Maria Udorah, Chinedu Arthur Idoko, Anthony N Ikefuna, Ifeoma J Emodi, Barth F Chukwu, Ndubuisi A Uwaezuoke, Osita U Ezenwosu, Ifeyinwa L Ezenwosu, Christopher Bismarck Eke |
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| Rok vydání: | 2021 |
| Předmět: |
Parents
Pediatrics medicine.medical_specialty Adolescent Nigeria Anemia Sickle Cell Adolescents RJ1-570 Factors Teaching hospital Disease severity Medicine Humans Socioeconomic status Children Depression (differential diagnoses) Sickle cell business.industry Depression Psychological evaluation Cross-Sectional Studies Pediatrics Perinatology and Child Health business Limited resources Research Article |
| Zdroj: | BMC Pediatrics BMC Pediatrics, Vol 21, Iss 1, Pp 1-8 (2021) |
| DOI: | 10.21203/rs.3.rs-294737/v1 |
| Popis: | Background Sickle cell anaemia (SCA) is the commonest monogenic haematologic disorder resulting from the inheritance of homozygous mutant haemoglobin genes from both parents. Some factors have been identified as important in explaining the variability in depression in sickle cell anaemia (SCA). Information on this is limited in a resource-limited setting like Nigeria. This study aims to determine factors which influence depression in children and adolescents with sickle cell anaemia in a resource-limited setting. Methods Systematic random sampling technique was used in this cross-sectional study to select children and adolescents aged 7–17 years at the weekly sickle cell clinic of the University of Nigeria Teaching hospital (UNTH) Enugu, Nigeria. Pretested, structured questionnaire was used to collect sociodemographic and disease severity data while depression was assessed using the Children’s Depression Inventory. Results Age and educational level had significant positive linear relationships with depression (r = 0.253, p = 0.02; r = 0.225, p = 0.04 respectively) while gender (χ2 = 0.531, p = 0.466), socioeconomic status (χ2 = 0.451, p = 0.798) and disease severity (χ2 = 0.422, p = 0.810) had no relationship with depression in children and adolescents with SCA. Conclusion Depression in children and adolescents with SCA increased with increasing age and educational level. Psychological evaluation should be integrated into routine assessment of children with SCA during their follow up visits as they get older and progress in class. |
| Databáze: | OpenAIRE |
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