Relationship between ciprofloxacin resistance and extended-spectrum β-lactamase production in Escherichia coli and Klebsiella pneumoniae strains

Autor: Ö. Auğ, Venüs Tolun, M. Anğ-Küçüker, Ö. Küçükbasmaci, Ç. Çatal, D. Törümküney-Akbulut
Rok vydání: 2004
Předmět:
Zdroj: Clinical Microbiology and Infection. 10(1):72-75
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2004.00723.x
Popis: Resistance to fluoroquinolones has increased markedly since their introduction. Mechanisms of resistance to any antibiotic class might play a role in resistance to an unrelated antibiotic class. This study evaluated the relationship between extended-spectrum β-lactamase (ESBL) production and ciprofloxacin resistance in Escherichia coli and Klebsiella pneumoniae strains isolated as causative agents of urinary tract infection. ESBL-producing strains were significantly more frequent among ciprofloxacin-resistant E. coli strains than among ciprofloxacin-susceptible E. coli strains (p = 0.015), but the difference was not significant among K. pneumoniae strains (p = 0.276).
Databáze: OpenAIRE