The Association of Mental Health over Time with Cardiac Outcomes in HEMO Study Patients
Autor: | Larissa Myaskovsky, Mary Amanda Dew, Khaled Abdel-Kader, Mark Unruh, Ea Wha Kang, Sarah J. Ramer, Francis Pike |
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Rok vydání: | 2012 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Heart Diseases Epidemiology medicine.medical_treatment Population Critical Care and Intensive Care Medicine Risk Assessment law.invention Randomized controlled trial Renal Dialysis Risk Factors law Cause of Death Surveys and Questionnaires Prevalence medicine Humans Prospective Studies Intensive care medicine education Prospective cohort study Survival analysis Aged Proportional Hazards Models Cause of death Transplantation education.field_of_study Proportional hazards model business.industry Original Articles Middle Aged Survival Analysis Mental health United States Hospitalization Logistic Models Mental Health Treatment Outcome Nephrology Multivariate Analysis Emergency medicine Kidney Failure Chronic Female Hemodialysis business |
Zdroj: | Clinical Journal of the American Society of Nephrology. 7:957-964 |
ISSN: | 1555-9041 |
Popis: | Summary Background and objectives Poor mental health over time is significantly associated with cardiovascular morbidity and mortality in the general population, which is the leading cause of death in dialysis patients. Most studies of dialysis patients, however, have investigated the relationship between baseline mental health measurements and all-cause mortality and not mental health measured longitudinally throughout a study and cause-specific mortality. Design, setting, participants, & measurements This study examined the association of changes in mental health over time with all-cause and cause-specific deaths and cardiac hospitalizations in the Hemodialysis study patients. Mental health was assessed at baseline and annually during the study with short form 36 mental health index scores. Poorer mental health was defined by a mental health index score≤60. Results Patients with poorer mental health at baseline were more likely to have less than a high school education and be unmarried, have significantly higher index of coexistent disease scores, and report taking β-blockers and sleep medications. Low mental health scores over time were independently associated with a decrease in survival time from all-cause mortality by −0.06 (−0.10, −0.03; P P =0.01) and composite of first cardiac hospitalization or cardiac death by −0.04 (−0.07, −0.02; P Conclusions This study found an independent association between poor mental health over time and all-cause mortality, cardiac hospitalization, and the composite of cardiac death or cardiac hospitalization in hemodialysis patients. The results underscore the importance of attention to mental health related to cardiac complications and even death in dialysis patients. |
Databáze: | OpenAIRE |
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