Clinical evaluations of autologous fibrin glue and polyglycolic acid sheets as oral surgical wound coverings after partial glossectomy
| Autor: | Shiro Mori, Kensuke Yamauchi, Hitoshi Miyashita, Wataru Hashimoto, Shinnosuke Nogami, Atsumu Kouketsu, Tetsu Takahashi, Jun Kurihara, Minami Fujiwara, Tadashi Kawai, Keisuke Higuchi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Open wounds medicine.medical_treatment Surgical Wound Partial glossectomy Fibrin Tissue Adhesive Adhesion (medicine) Postoperative Hemorrhage 03 medical and health sciences 0302 clinical medicine otorhinolaryngologic diseases medicine Humans Fibrin glue Aged Glossectomy business.industry Surgical wound 030206 dentistry Middle Aged medicine.disease Sutureless Surgical Procedures Surgery Otorhinolaryngology Coagulation 030220 oncology & carcinogenesis Female Tissue Adhesives Oral Surgery business Polyglycolic Acid |
| Zdroj: | Journal of Cranio-Maxillofacial Surgery. 44:964-968 |
| ISSN: | 1010-5182 |
| DOI: | 10.1016/j.jcms.2016.05.022 |
| Popis: | Polyglycolic acid (PGA) sheets and commercial fibrin glue are commonly used to cover open wound surfaces in oral surgery. Compared to commercial fibrin glue composed of pooled allogeneic blood, autologous fibrin glue is less expensive and poses lower risks of viral infection and allergic reaction. Here, we evaluated postoperative pain, scar contracture, ingestion, tongue dyskinesia, and postoperative bleeding in 24 patients who underwent partial glossectomy plus the application of a PGA sheet and an autologous fibrin glue covering (autologous group) versus 11 patients in whom a PGA sheet and commercial fibrin glue were used (allogeneic group). The evaluated clinical measures were nearly identical in both groups. Remarkable wound surface granulation was recognized in two cases in the autologous group. No complications were observed in either group, including viral infection or allergic reaction. Abnormal postoperative bleeding in the wound region was observed in one case in the allogeneic group. Coagulation and adhesion of the autologous fibrin glue were equivalent to those of conventional therapy with a PGA sheet and commercial fibrin glue. Thus, our results show that covering wounds with autologous fibrin glue and PGA sheets may help avoid the risks of viral infection and allergic reaction in partial glossectomy cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect