Backstage of eating disorder : about the biological mechanisms behind the symptoms of anorexia nervosa
| Autor: | Barbara Bętkowska-Korpała, Emil Dadański, Kamil Skowron, Krzysztof Gil, Magdalena Kurnik-Łucka |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Psychotherapist Endocrine System lcsh:TX341-641 Clinical settings Review eating disorders Disease anorexia nervosa Feeding and Eating Disorders 03 medical and health sciences 0302 clinical medicine medicine Humans microbiome–gut–brain axis Nutrition and Dietetics business.industry starvation neuropeptides Brain medicine.disease Hormones Gastrointestinal Microbiome hyperactivity Eating disorders 030104 developmental biology Anorexia nervosa (differential diagnoses) business lcsh:Nutrition. Foods and food supply 030217 neurology & neurosurgery Food Science |
| Zdroj: | Nutrients, Vol 12, Iss 2604, p 2604 (2020) Nutrients |
| Popis: | Anorexia nervosa (AN) represents a disorder with the highest mortality rate among all psychiatric diseases, yet our understanding of its pathophysiological components continues to be fragmentary. This article reviews the current concepts regarding AN pathomechanisms that focus on the main biological aspects involving central and peripheral neurohormonal pathways, endocrine function, as well as the microbiome–gut–brain axis. It emerged from the unique complexity of constantly accumulating new discoveries, which hamper the ability to look at the disease in a more comprehensive way. The emphasis is placed on the mechanisms underlying the main symptoms and potential new directions that require further investigation in clinical settings. |
| Databáze: | OpenAIRE |
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