Antioxidant and Antityrosinase Activity ofFlemingia macrophyllaandGlycine tomentellaRoots
| Autor: | Li-Ying Chen, Lih-Jeng Juang, Huo-Mu Tai, Bor-Sen Wang, Ming-Hsing Huang, Jeng-Jer Yang |
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| Rok vydání: | 2012 |
| Předmět: |
Antioxidant
Article Subject Traditional medicine biology Tyrosinase medicine.medical_treatment Daidzein Genistein lcsh:Other systems of medicine Isoflavones lcsh:RZ201-999 biology.organism_classification chemistry.chemical_compound Complementary and alternative medicine chemistry Genistin medicine Daidzin Flemingia macrophylla Research Article |
| Zdroj: | Evidence-based Complementary and Alternative Medicine : eCAM Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012) |
| ISSN: | 1741-4288 1741-427X |
| DOI: | 10.1155/2012/431081 |
| Popis: | The antioxidant and antityrosinase activities of the water extract ofFlemingia macrophyllaroot (WEFM) were investigated. The results showed that WEFM exhibited radical scavenging and reducing activities, as well as ferrous ion chelating property. In addition, WEFM also protected phospholipids against oxidation, indicating that WEFM could protect biomolecules from oxidative damage. Meanwhile, in the range of 50–100 μg/mL, the tyrosinase inhibitory activity of WEFM increased with an increase in sample concentration and was superior to that of the water extract ofGlycine tomentellaroot (WEGT). A high performance liquid chromatography analysis was used to determine the phenolic components, revealing that daidzin, daidzein, genistin, and genistein were present in WEFM and WEGT. Acting as an antioxidant and a tyrosinase inhibitor, these bioactive constituents could contribute to the protective effects of WEFM. Overall, the results showed that WEFM might serve as a natural antioxidant and tyrosinase inhibitor. |
| Databáze: | OpenAIRE |
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