The effects of biological sex and cardiovascular disease on COVID-19 mortality

Autor:	Maria Elena Hernandez-Hernandez, Robert Y. L. Zee, Patricia Pulido-Perez, Enrique Torres-Rasgado, Jose R. Romero
Rok vydání:	2022
Předmět:	Male Cardiovascular Diseases Risk Factors SARS-CoV-2 Physiology Physiology (medical) COVID-19 Humans Female Comorbidity Hospital Mortality Cardiology and Cardiovascular Medicine
Zdroj:	American Journal of Physiology-Heart and Circulatory Physiology. 323:H397-H402
ISSN:	1522-1539 0363-6135
DOI:	10.1152/ajpheart.00295.2022
Popis:	Cardiovascular disease (CVD) is a common comorbidity observed in patients with coronavirus disease 2019 (COVID-19), which is associated with increased severity and mortality. However, the effects of biological sex on CVD-associated mortality in patients with COVID-19 are poorly established, particularly among Hispanic/Latin Americans. We examined the association of preexisting CVD with COVID-19 mortality in hospitalized Latin American men and women. This multicenter study included Mexican patients hospitalized with a positive diagnosis of COVID-19. The main outcome was in-hospital mortality. Multivariable regression analyses were used to calculate the adjusted odds ratio with 95% confidence interval for mortality in women and men. Of 81,400 patients with a positive diagnosis for SARS-CoV-2 infection, 28,929 (35.54%) hospitalized patients were evaluated. Of these, 35.41% (10,243) were women. In-hospital death was higher in men than in women. In relation to CVD between the sexes, women had a higher incidence of CVD than men (4.69 vs. 3.93%
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f8642608a3ba6072b56594e550dea6 https://doi.org/10.1152/ajpheart.00295.2022 Zobrazit plný text záznamu