Effects of Aspirin on Blood Plasma Levels of Testosterone, LH and FSH in Maturing Male Rats
| Autor: | A. K. Didolkar, D. Roychowdhury, U. M. Joshi, A. Gurjar, Anil R. Sheth |
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| Rok vydání: | 1980 |
| Předmět: |
Male
medicine.medical_specialty Urology Endocrinology Diabetes and Metabolism Acid Phosphatase Ascorbic Acid Andrology Follicle-stimulating hormone Internal medicine Testis Blood plasma medicine Animals Testosterone Aspirin business.industry Prostate Organ Size Luteinizing Hormone Ascorbic acid Rats Cholesterol Endocrinology Reproductive Medicine Prostatic acid phosphatase Follicle Stimulating Hormone business Luteinizing hormone Hormone medicine.drug |
| Zdroj: | International Journal of Andrology. 3:312-318 |
| ISSN: | 1365-2605 0105-6263 |
| DOI: | 10.1111/j.1365-2605.1980.tb00121.x |
| Popis: | Effects of aspirin administration (5 mg/100 g body weight) for various days were observed on the hormonal levels of maturing male rats. Aspirin was given orally every day for 8, 15, 22 and 30 days. No change in the weights of testes, epididymis, prostate or seminal vesicles was observed after treatment. While aspirin administration for 8 days caused an increase in the plasma testosteone level with decrease in both LH and FSH levels, prolonged treatment for 15 days and more produced a reverse effect, viz. decrease in plasma testosterone and increase in plasma LH and FSH levels. Testicular ascorbic acid content was found to decrease on the 15th and the 22nd day of treatment. Testicular cholesterol was increased after 22nd and 30th days of treatment. Prostatic acid phosphatase activity decreased in all the treated groups. The possible significance of these findings is discussed. |
| Databáze: | OpenAIRE |
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