Blue-Light-Triggered Photorelease of Active Chemicals Captured by the Flavoprotein Dodecin
| Autor: | Martin Grininger, Gilbert Nöll, Sibylle Trawöger, Bernhard Dick, Madlene von Sanden-Flohe |
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| Rok vydání: | 2009 |
| Předmět: |
Halobacterium salinarum
Light Photochemistry Protein Conformation Riboflavin Color Flavoprotein Flavin group Biochemistry Riboflavin binding Protein structure heterocyclic compounds Binding site Molecular Biology Blue light Binding Sites Flavoproteins Molecular Structure biology Chemistry digestive oral and skin physiology Organic Chemistry food and beverages biology.organism_classification biology.protein Molecular Medicine Oxidation-Reduction human activities |
| Zdroj: | ChemBioChem. 10:834-837 |
| ISSN: | 1439-7633 1439-4227 |
| DOI: | 10.1002/cbic.200900014 |
| Popis: | Learning from nature: In nature, riboflavin binding proteins are responsible for the transport and release of riboflavin. Here, the development of a molecular photorelease system based on the riboflavin binding protein dodecin is presented. Any drug or active chemical linked to a flavin can be captured by dodecin and transported to a location of interest. Irradiation with blue light results in the release of the ligands. |
| Databáze: | OpenAIRE |
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