Cyst infection in hospital-admitted autosomal dominant polycystic kidney disease patients is predominantly multifocal and associated with kidney and liver volume

Autor: J. B. Dettoni, Luiz F. Onuchic, Bruno Eduardo Pedroso Balbo, Isac de Castro, C. R. Ono, Marcelo Tatit Sapienza, S. K. Jayanthi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Male
Pathology
Physiology
Cyst infection
Kidney
Biochemistry
Gastroenterology
Immunoenzyme Techniques
Cyst
General Pharmacology
Toxicology and Pharmaceutics
lcsh:QH301-705.5
lcsh:R5-920
Incidental Findings
medicine.diagnostic_test
Cysts
General Neuroscience
General Medicine
Middle Aged
Polycystic Kidney
Autosomal Dominant
Hospitalization
medicine.anatomical_structure
C-Reactive Protein
Liver
Female
medicine.symptom
lcsh:Medicine (General)
Brazil
Adult
medicine.medical_specialty
Immunology
Biophysics
Autosomal dominant polycystic kidney disease
Ocean Engineering
Kidney Volume
Positron-emission tomography/computed tomography
Sensitivity and Specificity
Statistics
Nonparametric
Internal medicine
Dysuria
Weight Loss
medicine
Kidney volume
Humans
Clinical Investigation
Mortality
Hematuria
Retrospective Studies
Chi-Square Distribution
business.industry
Magnetic resonance imaging
Cell Biology
medicine.disease
Liver volume
lcsh:Biology (General)
Concomitant
Positron-Emission Tomography
Complication
business
Zdroj: Brazilian Journal of Medical and Biological Research v.47 n.7 2014
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 47, Issue: 7, Pages: 584-593, Published: 13 JUN 2014
Brazilian Journal of Medical and Biological Research, Vol 47, Iss 7, Pp 584-593 (2014)
Popis: Positron-emission tomography/computed tomography (PET/CT) has improved cyst infection (CI) management in autosomal dominant polycystic kidney disease (ADPKD). The determinants of kidney and/or liver involvement, however, remain uncertain. In this study, we evaluated clinical and imaging factors associated with CI in kidney (KCI) and liver (LCI) in ADPKD. A retrospective cohort study was performed in hospital-admitted ADPKD patients with suspected CI. Clinical, imaging and surgical data were analyzed. Features of infected cysts were evaluated by PET/CT. Total kidney (TKV) and liver (TLV) volumes were measured by CT-derived multiplanar reconstruction. CI was detected in 18 patients who experienced 24 episodes during an interval of 30 months (LCI in 12, KCI in 10 and concomitant infection in 2). Sensitivities of CT, magnetic resonance imaging and PET/CT were 25.0, 71.4, and 95.0%. Dysuria (P
Databáze: OpenAIRE
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