Serological prevalence of echinococcosis and risk factors for infection among children in rural communities of southern Ningxia, China

Autor: Philip S. Craig, Ling Huang, Jing Teng, Tao Sun, Gail M. Williams, Wei Zhang, Malcolm K. Jones, Yu Rong Yang, Belgees Boufana, Dominique A. Vuitton, Patrick Giraudoux, Donald P. McManus, Yanbin Li, Tian Xi Liu
Přispěvatelé: Ningxia Medical College, Biomedical Sciences Research Institute, University of Salford, WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), Molecular Parasitology Unit, University of Queensland [Brisbane]-The Queensland Institute of Medical Research-Australian Centre for International and Tropical Health and Nutrition ( ACITH ), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Queensland Institute of Medical Research-University of Queensland [Brisbane]-Australian Centre for International and Tropical Health and Nutrition (ACITH)
Rok vydání: 2008
Předmět:
Prevalence
Rural Health
MESH : Echinococcus multilocularis
MESH: Epidemiologic Methods
MESH : Echinococcosis
MESH: Echinococcus granulosus
030308 mycology & parasitology
0302 clinical medicine
MESH : Child
Risk Factors
MESH: Risk Factors
MESH: Child
MESH : Rural Health
MESH : Socioeconomic Factors
MESH: Animals
Child
Echinococcus granulosus
0303 health sciences
biology
[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie
MESH : Risk Factors
Echinococcosis
MESH: China
3. Good health
[ SDE.MCG ] Environmental Sciences/Global Changes
Infectious Diseases
China
MESH: Socioeconomic Factors
Adolescent
[SDE.MCG]Environmental Sciences/Global Changes
030231 tropical medicine
Helminthiasis
MESH : Family Health
Echinococcus multilocularis
MESH : Epidemiologic Methods
MESH: Echinococcosis
03 medical and health sciences
MESH : Adolescent
Environmental health
parasitic diseases
medicine
Animals
Humans
MESH : China
Seroprevalence
Risk factor
Family Health
MESH: Adolescent
MESH: Echinococcus multilocularis
MESH: Humans
MESH : Echinococcus granulosus
business.industry
MESH : Humans
Public Health
Environmental and Occupational Health
MESH: Rural Health
medicine.disease
biology.organism_classification
Echinococcus
Socioeconomic Factors
MESH: Family Health
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Parasitology
MESH : Animals
Epidemiologic Methods
business
Zdroj: Tropical Medicine and International Health
Tropical Medicine and International Health, Wiley-Blackwell, 2008, 13 (8), pp.1086-94. 〈10.1111/j.1365-3156.2008.02101.x〉
Tropical Medicine and International Health, Wiley-Blackwell, 2008, 13 (8), pp.1086-94. ⟨10.1111/j.1365-3156.2008.02101.x⟩
ISSN: 1365-3156
1360-2276
DOI: 10.1111/j.1365-3156.2008.02101.x
Popis: International audience; OBJECTIVE: To assess the usefulness of serology as an indicator of Echinococcus transmission for developing preventive measures against echinococcosis in rural communities. METHODS: Cross-sectional survey in 2002 among 861 children aged 7 to 18 years in Xiji County, Ningxia, China. Before ultrasound abdominal examination, a questionnaire was used to identify socioeconomic, sanitary and hygiene risk factors for echinococcal infection; filter paper blood samples were collected from each child for specific antibody detection using EmP (Echinococcus multilocularis) and EgB (Echinococcus granulosus) antigens. RESULTS: Transmission of both E. multilocularis and E. granulosus occur in this area. Serological prevalence was far higher than disease prevalence in this age range. We found no gender-related differences of seroprevalence among the children, suggesting an equal chance of exposure to echinococcal egg-contaminated environments. The seroprevalence distribution was associated with changes in the ecology of wild hosts for E. multilocularis contamination, and with changes in socio-geographic features of the communities for E. granulosus contamination. CONCLUSIONS: Serological data obtained for children in mass surveys of echinococcosis appear to be a comprehensive and useful tool to monitor changes of transmission dynamics in humans and provide 'warning signals' to decision makers for the instigation of specific control measures against the disease.
Databáze: OpenAIRE
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