Isolation of phytoconstituents and evaluation of biological potentials of Berberis hispanica from Algeria
| Autor: | Khellaf Rebbas, Labib Noman, Ilham Bencherchar, Samira Benyahia, Fadila Benayache, Ibrahim Demirtas, Samir Benayache, Feyza Oke-Altuntas, Redouane Lemoui |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pharmacology
Traditional medicine biology lcsh:RM1-950 010401 analytical chemistry 02 engineering and technology 021001 nanoscience & nanotechnology medicine.disease biology.organism_classification Antimicrobial 01 natural sciences 0104 chemical sciences HeLa chemistry.chemical_compound Tamarixetin Rutin lcsh:Therapeutics. Pharmacology chemistry Berberis hispanica Caffeic acid medicine Butylated hydroxytoluene Klebsiella pneumonia 0210 nano-technology |
| Zdroj: | Bangladesh Journal of Pharmacology, Vol 13, Iss 2 (2018) |
| ISSN: | 1991-0088 |
| Popis: | The aim of this study was to isolate the phytoconstituents and evaluate the biological activities of Berberis hispanica. Three phenolic compounds (tamarixetin, caffeic acid and rutin) were isolated from B. hispanica. The structures of the pure compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR, and HPLC-TOF/MS. In addition, antimicrobial, anti-oxidant and anti-proliferative effects of the extracts, some fractions and isolated compounds were evaluated. The extracts of B. hispanica were evaluated against six bacterial strains and exhibited the highest activity against Klebsiella pneumonia (15 mm at 100 mg/mL). Fraction T36 (IC50 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|