Immobilization and Light-Dark Cycle-Induced Modulation of Serotonin Metabolism in Rat Brain and of Lymphocyte Subpopulations: In vivo Voltammetric and FACS Analyses
| Autor: | C. Hasse, F. Schäfer, N. Weiner, J. Heymanns, Wolfgang Wesemann, D. Gemsa, H. W. Clement, K. Pohlner |
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| Rok vydání: | 1993 |
| Předmět: |
Male
Serotonin medicine.medical_specialty Light Lymphocyte Cell Separation Biology Serotonergic Immobilization In vivo Internal medicine medicine Animals Circadian rhythm Biological Psychiatry Brain Chemistry Raphe T-Lymphocytes Helper-Inducer T lymphocyte Metabolism Darkness Hydroxyindoleacetic Acid Flow Cytometry Lymphocyte Subsets Rats Psychiatry and Mental health Neuropsychology and Physiological Psychology medicine.anatomical_structure Endocrinology Rats Inbred Lew Extracellular Space Stress Psychological |
| Zdroj: | Neuropsychobiology. 28:91-94 |
| ISSN: | 1423-0224 0302-282X |
| Popis: | The effect of immobilization and light-dark cycle on the serotoninergic system of the n. raphe dorsalis and on the distribution of blood lymphocyte subpopulations was studied in the rat. As was shown by in vivo voltammetry, 10 min immobilization enhanced serotonin metabolism with a maximum 15 min after immobilization. The distribution of the blood lymphocytes into subpopulations was also affected: pan-T and T helper lymphocytes were reduced during immobilization and reached minimum values after 20 min recovery. The circadian rhythms of serotonin metabolism and the distribution of pan-T and T helper cells exhibited a slight phase shift if compared with each other. |
| Databáze: | OpenAIRE |
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