Cutaneous squamous cell carcinoma is associated with Lynch syndrome: widening the spectrum of Lynch syndrome-associated tumours
| Autor: | Berbel L. M. Ykema, E. Dekker, M E van Leerdam, Marianne B. Crijns, Fonnet E. Bleeker, F. Adan, Petur Snaebjornsson, M. W. Bekkenk |
|---|---|
| Přispěvatelé: | Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Dermatology, CCA - Cancer biology and immunology |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Skin Neoplasms
Cutaneous squamous cell carcinoma business.industry Dermatology medicine.disease Colorectal Neoplasms Hereditary Nonpolyposis Lynch syndrome stomatognathic diseases 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Increased risk Germline mutation Skin tumours Carcinoma Squamous Cell Cancer research medicine Humans DNA mismatch repair business |
| Zdroj: | British journal of dermatology, 185(2), 462-463. Wiley-Blackwell |
| ISSN: | 0007-0963 |
| Popis: | Dear Editor, Lynch syndrome (LS) is caused by a germline mutation in one of the mismatch repair (MMR) genes. Individuals with LS have an increased risk of developing colorectal and many other tumours including skin tumours.1 Sebaceous neoplasms and keratoacanthomas are skin tumours associated with LS, also known as Muir-Torre syndrome. For cutaneous squamous cell carcinoma (SCC), an association with LS has been suggested. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text