| Autor: |
Yusuke Konta, Eiichiro Saito, Koji Sato, Kyohei Furuta, Kenichiro Miyauchi, Akiko Furukawa, Hiroshi Sato, Tae Yamamoto |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Internal medicine (Tokyo, Japan). 61(21) |
| ISSN: |
1349-7235 |
| Popis: |
We herein report a case of acute kidney injury (AKI) due to tubulointerstitial nephritis (TIN) after starting empagliflozin in a diabetic patient. The patient developed stage 1 AKI with proteinuria and elevated tubulointerstitial markers. A renal biopsy showed acute TIN with lymphocytic infiltration into the interstitium. The patient's renal function improved after discontinuation of empagliflozin and steroid administration. Sodium-glucose cotransporter 2 (SGLT2) inhibitor-induced AKI has been reported, but the underlying mechanism remains unclear, potentially because few patients with SGLT2-inhibitor-induced AKI have undergone a renal biopsy. We report the present case in the hope that it will help clarify the mechanism. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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