Population dynamics and chemotherapeutic control of Trichuris trichiura infection of children in Jamaica and St. Lucia
| Autor: | D.A.P. Bundy, Roy M. Anderson, E.S. Cooper, M.H.N. Golden, D.E. Thompson |
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| Rok vydání: | 1985 |
| Předmět: |
Male
Jamaica Veterinary medicine Trichuriasis West Indies Population Dynamics Population Models Biological Feces Recurrence medicine Humans Child Infected population education Parasite Egg Count education.field_of_study biology business.industry Ascaris Age Factors Public Health Environmental and Occupational Health Infant General Medicine biology.organism_classification medicine.disease Chemotherapy regimen Trichuris trichiura Infections Mebendazole Trichuris Infectious Diseases Child Preschool Trichuris trichiura Female Parasitology business Basic reproduction number Demography |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 79:759-764 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/0035-9203(85)90110-5 |
| Popis: | Population dynamical parameters of Trichuris trichiura infections in children were estimated from longitudinal intensity and prevalence data from a population (n = 23) in a children's home in Jamaica. The theoretical predictions of a deterministic model incorporating these parameters were approximated to observed horizontal-age prevalence data from a naturally infected population (n = 203) of children in a St. Lucian village, and a rough estimate of the basic reproductive rate (Ro = 8-10) of T. trichiura obtained. The findings suggest that T. trichiura populations are intrinsically more difficult to control by traditional mass-treatment chemotherapy (eradication requires greater than 91% of the population to be treated every 6 months for greater than 5 years) than are populations of Ascaris, but may be more susceptible to selective chemotherapy programmes which aim to treat only the most heavily infected individuals. |
| Databáze: | OpenAIRE |
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