Analysis of cases with tuberculous peritonitis: a single-center experience
| Autor: | Rafet Mete, M Kürşat Türkdoğan, Bilge Gültepe, Davut Demirkiran, Sevdegul Karadas, A. Cumhur Dulger |
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| Přispěvatelé: | SÜMBÜL, BİLGE |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Abdominal pain Tuberculosis Adolescent Turkey Adenosine Deaminase Antitubercular Agents Peritonitis Tuberculous Prevalence Peritonitis Gastroenterology Mycobacterium tuberculosis Young Adult Internal medicine Ascites medicine Humans Retrospective Studies biology business.industry Mortality rate Middle Aged biology.organism_classification medicine.disease Surgery Socioeconomic Factors CA-125 Antigen Female Laparoscopy Differential diagnosis medicine.symptom business |
| Popis: | Background/aims Tuberculous peritonitis (TP) is a rare form of tuberculosis and is caused by peritoneal involvement with Mycobacterium tuberculosis. A distinctive correlation exists between socioeconomic state and disease prevalence. We aimed to evaluate the clinical, laboratory, and radiological findings of patients with TP. Materials and methods We conducted a retrospective study in patients with peritoneal tuberculosis from January 2004 to October 2008 at Yuzuncu Yil University Medical School Education and Research Hospital. During this time, the data of 21 patients (17 females) with TP were reviewed. Results Fever, abdominal pain, and anorexia were the most common symptoms. An analysis of ascites showed lymphocyte predominance and low albumin gradient in all patients. Patients with TP had a median ascites adenosine deaminase (ADA) level of 139 U/L (range, 25 to 303U/L). Peritoneal involvement (wet peritonitis) was seen in all the cases. Following 6-month administration of combined anti-TBC treatment, mean serum CA-125 levels were within the normal range among patients who had previously higher serum CA-125 level. Mortality rate in the total cases was 4.6%. Conclusion Peritoneal tuberculosis should be considered in the differential diagnosis of exudative ascites in eastern Turkey. A high level of suspicion is required, especially in high-risk populations living in rural areas. ADA seems to be a sufficient, safe, and inexpensive method to perform the diagnosis of peritoneal tuberculosis. Serum CA-125 levels may play a key role to support the diagnosis as well as disease management of TP. |
| Databáze: | OpenAIRE |
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