Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction
| Autor: | Dario Leosco, Lucia Visaggi, Leonardo Bencivenga, Ilaria Ronga, Bruno Trimarco, Carmine Morisco, Klara Komici, Sandra Provenzano, Nicola Ferrara, Antonio Cittadini, Dino Franco Vitale, Fabrizio Vincenzo Grieco, Graziamaria Corbi, Maddalena Conte, Angela Mancini, Giuseppe Rengo |
|---|---|
| Přispěvatelé: | Komici, Klara, Vitale, Dino Franco, Mancini, Angela, Bencivenga, Leonardo, Conte, Maddalena, Provenzano, Sandra, Grieco, Fabrizio Vincenzo, Visaggi, Lucia, Ronga, Ilaria, Cittadini, Antonio, Corbi, Graziamaria, Trimarco, Bruno, Morisco, Carmine, Leosco, Dario, Ferrara, Nicola, Rengo, Giuseppe |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Population Psychological intervention Myocardial Infarction Renal function Nutritional Status acute myocardial infarction lcsh:TX341-641 030204 cardiovascular system & hematology elderly Article 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Troponin I Medicine Humans 030212 general & internal medicine Myocardial infarction education Geriatric Assessment Aged Aged 80 and over education.field_of_study mini nutritional assessment mortality Food Science Nutrition and Dietetics business.industry Malnutrition Nutritional status medicine.disease Blood pressure Nutrition Assessment Female business lcsh:Nutrition. Foods and food supply |
| Zdroj: | Nutrients, Vol 11, Iss 2, p 224 (2019) Nutrients Volume 11 Issue 2 |
| Popis: | Background: Malnutrition is a frequent condition in the elderly, and is associated with prolonged hospitalization and increased mortality. However, the impacts of malnutrition among elderly patients with acute myocardial infarction have not been clarified yet. Methods and Results: We enrolled 174 patients aged 65 years and over, admitted with the diagnosis of acute myocardial infarction (AMI), who underwent evaluation of nutritional status by Mini Nutritional Assessment (MNA) and evaluation of mortality risk by GRACE Score 2.0. All-cause mortality was the outcome considered for this study. Over a mean follow-up of 24.5 ± 18.2 months, 43 deaths have been registered (24.3%). Non-survivors were more likely to be older, with worse glomerular filtration rate, lower systolic blood pressure, lower albumin and MNA score, higher prevalence of Killip classification III-IV grade, and higher Troponin I levels. Multivariate Cox proportional analysis revealed that GRACE Score and MNA showed a significant and independent impact on mortality, (HR = 1.76, 95%, CI = 1.34&ndash 2.32, and HR = 0.56, 95% CI = 0.42&ndash 0.73, respectively). Moreover, the clinical decision curve revealed a higher clinical net benefit when the MNA was included, compared to the partial models without MNA. Conclusion: Nutritional status is an independent predictor of long-term mortality among elderly patients with AMI. MNA score in elderly patients with AMI may help prognostic stratification and identification of patients with, or at risk of, malnutrition in order to apply interventions to improve nutritional status, and maybe survival in this population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|