Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan

Autor: Muh Yong Yen, Chen Yuan Chiang, Tao Ping Lin, Ming Chih Yu, Kuan Jen Bai, Shiang Lin Yang, Yu Ling Hsu, Hsiu Chen Shih
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Bacterial Diseases
Male
Non-Clinical Medicine
Pulmonology
Health Care Providers
Antitubercular Agents
lcsh:Medicine
Pharmacology
Medicine
Practice Patterns
Physicians'
lcsh:Science
Allied Health Care Professionals
Multidisciplinary
Isoniazid
Middle Aged
Lower Respiratory Tract Infections
Drug Combinations
Infectious Diseases
Practice Guidelines as Topic
Drug Therapy
Combination
Female
Rifampin
Research Article
medicine.drug
Adult
medicine.medical_specialty
Tuberculosis
Infectious Disease Control
Dose
Taiwan
Drug Prescriptions
Young Adult
Pharmacotherapy
Internal medicine
Humans
Dosing
Health Care Quality
Aged
Dose-Response Relationship
Drug
business.industry
Health Services Administration and Management
Body Weight
lcsh:R
Pyrazinamide
medicine.disease
Relative risk
Respiratory Infections
lcsh:Q
business
Rifampicin
Zdroj: PLoS ONE, Vol 7, Iss 8, p e44133 (2012)
PLoS ONE
ISSN: 1932-6203
Popis: Background It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007–2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings Lists of all notified culture positive TB cases in 2007–2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007–2010 (p
Databáze: OpenAIRE
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