Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan
Autor: | Muh Yong Yen, Chen Yuan Chiang, Tao Ping Lin, Ming Chih Yu, Kuan Jen Bai, Shiang Lin Yang, Yu Ling Hsu, Hsiu Chen Shih |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
Bacterial Diseases
Male Non-Clinical Medicine Pulmonology Health Care Providers Antitubercular Agents lcsh:Medicine Pharmacology Medicine Practice Patterns Physicians' lcsh:Science Allied Health Care Professionals Multidisciplinary Isoniazid Middle Aged Lower Respiratory Tract Infections Drug Combinations Infectious Diseases Practice Guidelines as Topic Drug Therapy Combination Female Rifampin Research Article medicine.drug Adult medicine.medical_specialty Tuberculosis Infectious Disease Control Dose Taiwan Drug Prescriptions Young Adult Pharmacotherapy Internal medicine Humans Dosing Health Care Quality Aged Dose-Response Relationship Drug business.industry Health Services Administration and Management Body Weight lcsh:R Pyrazinamide medicine.disease Relative risk Respiratory Infections lcsh:Q business Rifampicin |
Zdroj: | PLoS ONE, Vol 7, Iss 8, p e44133 (2012) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Background It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007–2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings Lists of all notified culture positive TB cases in 2007–2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007–2010 (p |
Databáze: | OpenAIRE |
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