Complete Resolution of Wegener’s Granulomatosis Lung Granuloma After Aortic Root Replacement
| Autor: | Sarah-Jayne Edmondson, Saina Attaran, Ulrich P. Rosendahl |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Aortic dissection
medicine.medical_specialty Pathology business.industry Aortic root Case Report Inflammation medicine.disease Surgery law.invention Dissection law Granuloma Deep hypothermic circulatory arrest medicine Cardiopulmonary bypass Radiology Nuclear Medicine and imaging medicine.symptom Cardiology and Cardiovascular Medicine business Systemic vasculitis |
| Zdroj: | AORTA. :25-28 |
| ISSN: | 2325-4637 |
| DOI: | 10.12945/j.aorta.2015.15.009 |
| Popis: | Wegner’s granulomatosis (WG) is an autoimmune systemic vasculitis that results in necrotizing granulomas. We report a WG patient with a lung granuloma and aortic root dilatation, who underwent aortic root replacement on cardiopulmonary bypass (CPB). Intraoperatively, the patient suffered an aortic dissection, which was repaired immediately under deep hypothermic circulatory arrest (DHCA). Follow-up imaging showed complete granuloma resolution, despite absence of immunosuppressive therapy. Immune stimulation following CPB is well described; here, the opposite was observed and DHCA effects are discussed. |
| Databáze: | OpenAIRE |
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